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Caryn Oshiro, PhD, MS, RD
Collaborative Investigator
Contact Info
Email: Caryn.ES.Oshiro@kp.org
Phone: (808) 432-5777 x1939

Caryn Oshiro, PhD, MS, RD is a collaborative investigator at CIHR who uses a life-course approach to studying obesity as a chronic progressive disease and its relationship to other chronic diseases, including cardiovascular disease, diabetes, and cancer. She also studies the impacts of new and effective pharmacological treatments for obesity and diabetes on patient health and lifestyle (nutrition and physical activity).

Much of Dr. Oshiro’s current research centers on maternal and child health, including research on the impact of gestational diabetes screening on adverse pregnancy outcomes, and the relationship between preconception, pregnancy, and infancy weight trajectories on childhood obesity. This work has included her role as KPHI Principal Investigator on the innovative GO MOMs study, which is using continuous glucose monitoring during pregnancy to investigate the relationship between metabolic outcomes in mothers and their offspring. Dr. Oshiro also studies the roles of racial and ethnic disparities and food insecurity in biopsychosocial health throughout the life course.

Dr. Oshiro joined CIHR in 2006 and has developed deep expertise in using electronic health record data to examine health disparities in obesity, diabetes, and cancer; screening for chronic diseases and other conditions within health care systems; understanding predictors of healthy aging in the older adult using risk prediction models; and conducting large, pragmatic, randomized trials of disease screening and prevention interventions in underserved populations. She has also led NIH- and PCORI-funded multi-site projects as site PI. These projects have ranged from large, longitudinal cohort studies to health behavior interventions. Locally, she has created collaborative research networks focused on cancer and nutritional studies with the University of Hawaii. She has worked with primary care providers at Kaiser Permanente Hawaii on efforts to understand prevalence of disease and health conditions and improve practice using electronic medical records data and research methodology.

Dr. Oshiro completed an MS in nutritional sciences and a PhD in epidemiology from the University of Hawaii; she is also a Registered Dietician and completed a clinical dietetic internship at the University of Michigan Hospitals in Ann Arbor. Her early experience as a clinical RD as part of interdisciplinary health care teams in the Michigan, Adventist Health, and Kaiser Permanente health care systems has given her invaluable clinical inpatient and outpatient expertise, as well as experience working with diverse populations. Now, as a researcher connected to the health care system, she uses both her epidemiologic and clinical experience to translate research into knowledge for use by health care providers and the broader community.

Selected Publications:

Full List of Publications:

Studies:

MATTRACK: THE IMPACT OF PRECONCEPTION MATERNAL WEIGHT TRAJECTORIES ON MATERNAL, PREGNANCY, AND CHILD OUTCOMES

MatTrack is an electronic medical record - based retrospective study of pregnant individuals selected from various Kaiser Permanente health care systems. The objective of this study is to examine the impact of maternal preconception weight trajectories on pregnancy weight gain and retention, pregnancy outcomes, and child outcomes.

Sponsor: NIH/NIDDK

Subcontract to: Center for Health Research, Kaiser Permanente Northwest

KPHI Co-Investigator: Caryn Oshiro, PhD

POSIT: PRECONCEPTION BARIATRIC SURGERY AND CHILD HEALTH OUTCOMES STUDY

The POSIT study aims to estimate the effects of preconception weight loss by maternal metabolic-bariatric surgery on infant and child body size, growth, and related outcomes. The study cohort is sampled from Kaiser Permanente health care systems located in the Pacific Northwest, Southern California, and Hawaii.

Sponsor: NIH/NIDDK

Subcontract to: Oregon Health & Science University (OHSU)

KPHI Principal Investigator: Caryn Oshiro, PhD

GOMOMS: CHARACTERIZING, BY TRIMESTER, CONTINUOUS GLUCOSE MONITORING MEASUREMENTS FOR DETERMINING EFFECTS ON MATERNAL & OFFSPRING METABOLIC SEQUELAE

Gestational diabetes (GDM) is a type of diabetes that develops during pregnancy and increases the risk of pregnancy and birth complications. New tests may allow doctors to identify women with GDM earlier and more accurately than the tests currently being used, but we need to understand them better. The GO MOMs study is recruiting 400 pregnant individuals and screening them using both traditional and new GDM screening tools at 12, 20, and 28 weeks of pregnancy to determine how well these tools identify people who are at risk of pregnancy complications and need treatment.

Sponsor: NIH/NIDDK

KPHI Principal Investigator: Caryn Oshiro, PhD

GO MOMS: NUTRITION STUDY

The GO MOMs Nutrition Study is an observational substudy nested within the GO MOMs study (described above). The goal of the study is to describe maternal diet quality and composition in a diverse cohort of pregnant individuals and to study the relationship between maternal diet and outcomes including maternal glycemia, maternal insulin physiology, infant birth weight, and infant fat mass.

Sponsor: NIH/Office of Nutrition Research

KPHI Principal Investigator: Caryn Oshiro, PhD

ON TARGET DM: COMPARISON OF TYPE 2 DIABETES PHARMACOTHERAPY REGIMENS USING TARGETED LEARNING

This study is using observational data from real-world clinical settings to directly compare the impacts of different Type 2 Diabetes treatment strategies on cardiovascular outcomes and other outcomes that are important to patients.

Sponsor: PCORI

KPHI Co-Investigator: Caryn Oshiro, PhD